Preclinical studies have shown their potential to reduce inflammation and modulate immune responses in diseases like rheumatoid arthritis and lupus.

The complement proteins C3 and protease factor B have a central role in the activation pathways of the complement system. Recent advances in the structural biology of complement protein C3 ...

These tests are intended to evaluate abnormalities in the alternative complement pathway. If the C3NeF assay is positive, plasma exchange or infusion should be considered, as should administration ...