The researchers' innovative approach involved two simple molecules: the amino acid cysteine and a short-chain choline thioester. Using silica glass as a mineral catalyst, they demonstrated that ...
The structure of complement protein C3 reveals a large, modular protein consisting of 13 domains with a buried thioester moiety. Proteolytic activation of C3 into C3b induces conformational ...
E1 enzymes facilitate conjugation of ubiquitin and ubiquitin-like proteins through adenylation, thioester transfer within E1, and thioester transfer from E1 to E2 conjugating proteins. Early work ...
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