Organoids were cultured from healthy donor iPSC sources and differentiated using the human iPSC-derived Cerebral Organoid ...

Adeno-associated viral (AAV) vectors in particular have high transduction rates and reduced toxicity concerns compared to other viral vectors. However, these delivery vehicles present some application ...

Viral gene delivery is a ubiquitous laboratory technique with a myraid of uses. Understanding the basics of gene delivery workflows, from vector selection and cloning to transduction, is a fundamental ...

To help investigators choose the optimum vector system for their proposed application, the Core has many in-stock vectors containing a range of reporters, which will provide essential information ...

One way to achieve non-viral transduction is by using electroporation to introduce single-strand (ssDNA) or double-strand DNA (dsDNA) into the cell. CAR T cells produced with such non-viral ...

Recent studies showed that a peptide, the protein transduction domain (PTD ... when expressed from viral vectors. The Tat motif allowed for mannose-6-phosphate (M6P) independent uptake in vitro ...

Viral vectors are engineered viruses that are used to deliver genetic material into cells for various applications, such as gene therapy, vaccine development, and biotechnology research. These viruses ...

Examining cells for eGFP expression following transduction with Ad5-CMV-eGFP using a fluorescent microscope is a quick method for estimating transduction efficiency. Ad5-CMV-Cre-eGFP expresses the Cre ...