Moderna (MRNA), once a pandemic-era darling, has seen its stock plummet 65% over the past year, battered by fading vaccine ...

Messenger RNA abundance is determined by balancing transcription and RNA decay. mRNA stability can be rapidly modulated to alter the expression of specific genes thereby providing flexibility in ...

microscope. Chinese tech giant Baidu Research has developed a revolutionary AI algorithm that significantly enhances the stability and antibody response of Covid-19 mRNA vaccines. The company’s ...

Nerve cells have amazing strategies to save energy and still perform the most important of their tasks. Researchers from the ...

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

When MARTRE1 was expressed in cells, it slowed the rate of poly(A) tail shortening and enhanced mRNA stability. Homology sequence analysis indicated that Martre1 belongs to a previously under ...

and post-transcriptional chemical modifications that affect RNA stability and immune activation. 2 In Mercer’s latest work published in Nature Communications, his team developed a streamlined method ...

Researchers are developing various delivery systems, such as lipid nanoparticles and viral vectors, to improve mRNA delivery and minimize off-target effects. Another challenge is the stability of mRNA ...

There have been 67 confirmed human bird flu cases in the U.S. since April 2024. Moderna has been awarded approximately $590 million from the federal government to help speed up the development of ...

2005-2010: Improvements in mRNA synthesis, purification, and stability through chemical modifications and sequence optimization. 2010-2015: Development of lipid nanoparticle delivery systems for ...