Purpose: The effects of extreme temperatures on drug delivery of two albuterol sulfate hydrofluoroalkane, metered-dose inhalers (MDIs) were evaluated.Methods. Three Proventil HFA and three ...

Seven Proventil HFA (albuterol sulfate 6.7 g hydrofluoroalkane inhalation aerosol) a and seven Ventolin HFA (albuterol sulfate 18 g hydrofluoroalkane inhalation aerosol) b MDIs were acquired from ...

Inhalers generally expire 1 year after they’re issued, but depending on how they’re stored, they may be good for months after that. If there’s any doubt, get a new one. You may wonder ...

Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, United States Food and Drug Administration (FDA), ...