Disruption of a single amino acid in a cellular protein makes breast cancer cells behave like stem cells
Vimentin is a type III intermediate filament (IF) protein normally expressed in cells that develop into connective tissue, ...
Science Daily1d
Drug may counteract muscle loss and osteoporosis after rapid weight loss
Rapid weight loss affects muscle mass and can increase the risk of osteoporosis. But now there is good news for people taking weight loss medication who may be at risk. A new study indicates that the ...
When blood cancer starts to spread, tumor cells diversify and affect immune response
When blood cancer cells break through the bone and multiply, tumor cells become dangerously diverse and the immune response ...
eLife2d
Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...