Daptomycin, a cyclic lipopeptide, was approved 10 years ago in the ... this is also the first time daptomycin's potential myotoxicity was confirmed by meta-analysis. Comparative subgroup analyses of ...

Subgroup analysis and modeled interaction terms was used to ... As, Arsenic; BKMR, Bayesian kernel machine regression; BMI, Body mass index; Cd, Cadmium; CGMP, Cyclic guanosine monophosphate; Co, ...

Background therapy with bosentan was present in 53% of study subjects, but statistically significant improvement in 6MWD was not achieved in the combination therapy subgroup ... of effective oral ...

11 This subgroup of patients also had much lower rates of functional ... There is an imbalance between platelet agonists, ADP and serotonin, and its inhibitor, cyclic adenosine monophosphate (cAMP) ...

The ER is an intracellular organelle consisting of a membranous network that extends throughout the cytoplasm of the cell and is contiguous with the nuclear envelope. In eukaryotic cells, the ER ...

Human neuroscience has always been pushing the boundary of what is measurable. During the last decade, concerns about statistical power and replicability – in science in general, but also specifically ...

Genomic instability and amplification are intrinsically important traits determining the development and heterogeneity of tumors. The role of extrachromosomal circular DNA (eccDNA) in tumors has ...

Sildenafil and tadalafil represent selective PDE-5i that target the nitric oxide pathway through prevention of the breakdown of cyclic GMP in the endothelium of the pulmonary vasculature. This in turn ...

Copyright: © 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. Myasthenia gravis is an ...

Correspondence to Dr Meredyth G Ll Wilkinson, Infection, Immunity and Inflammation Research and Teaching Department, UCL, London, WC1N1EH, UK; meredyth.wilkinson.14{at}ucl.ac.uk; Dr Elizabeth C Rosser ...

3 Cardiovascular Research Institute, Wayne State University School of Medicine, Detroit, Michigan, USA Correspondence to Dr David Viau, Department of Emergency Medicine, Wayne State University School ...