Subtle signs of neurodegeneration can be detected in blood, cerebrospinal fluid (CSF), and through neuroimaging, up to two decades before motor symptoms in Huntington’s disease (HD) present ...
A study published in Nature Medicine reveals subtle neurodegenerative changes in people with Huntington’s disease gene expansion up to 20 years before symptoms appear. Using advanced imaging, blood ...
The cells seem to die once the CAG repeat reaches about 150 times. As these mutation-carrying neurons die off, the symptoms of the disease arise. Therapies that aim to treat Huntington's by reducing ...
Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and ... Huntington’s symptoms – which include involuntary movement, unsteady gait, personality ...
A new study of nerve cells affected by Huntington’s disease (HD) reveals that the ... it doesn’t cause neurological symptoms until much later in life. The researchers, led by Steven McCarroll ...
The team found that although functions such as movement, thinking or behavior remained normal for a long time before the onset of symptoms in Huntington's disease, subtle changes to the brain were ...