Myeloid deficiency of the mitochondrial transacetylase tafazzin upregulates mtROS, disrupting UPR and calcium homeostasis, ...

Neutrophil granulocytes, a type of immune cell, are indispensable for the defense against pathogens. However, if they migrate into injured tissue, for example into the brain after a stroke, they can ...

The aim of this study was to investigate the functions of semaphorin 4D (SEMA4D) in regulation of neutrophil activation, and its involvement in AAV pathogenesis. Methods Serum levels of soluble SEMA4D ...

Conclusions These data reveal a novel neutrophil-intrinsic role for Card9 in arthritogenic Th17 responses and AS pathogenesis. These data provide valuable utility in our future understanding of ...

The impact of Card9 deletion on neutrophil function was assessed by an in vivo model of fungal infection and various functional assays, including endpoint dilution assay, apoptosis assay by flow ...

Mechanistic studies revealed BHLHE40, downstream to hypoxia and endoplasmic reticulum stress, was a key regulator in polarisation of neutrophils towards TAN-1 phenotype, and direct transcriptional ...

Additionally, a detailed ex vivo study of influence of pathogen, prosurvival mediators and current medications like ICS on neutrophil subset morphology, surface expressions and functional behaviour is ...

The following portable battery packs use the Surface proprietary charging port as their charging interface. It is compatible with all Surface devices, especially for older Surface devices that don't ...

Radiomics-based prediction of HCC response to atezolizumab/bevacizumab. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal Cancers Symposium. This ...

The State Department has suspended processing passport applications seeking the gender marker of “X” and will only process and issue passports for people identifying as male or female ...

Microsoft is set to reveal new devices in 2025, including a Surface Pro and Surface Laptop with smaller designs and Snapdragon X power, according to a recent report. Better yet, they're expected ...

Secretary of State Marco Rubio has frozen all applications for passports with “X” gender markers, an option available to people who don’t identify as male or female that was started in the ...