For example, CMA can detect trisomy 21 in a prenatal sample, but cannot identify its origin from a non-disjunction event or an unbalanced Robertsonian translocation. In cases of aneuploidies involving ...

Expert Rev Mol Diagn. 2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that ...

Recombination events in many organisms are concentrated in highly localized areas termed 'hot spots'. Hot spots can be detected by statistical analysis of genetic variation, analysis of pedigrees ...

Allopolyploids are common in natural ecosystems (Grant, 1981). They arise as a result of distant hybridization (and chromosome doubling) between related species containing different sets of related, ...