Response to humanized defucosylated anti-CCR4 antibody (KW-0761) in a representative patient with acute-type adult T-cell leukemia–lymphoma. The time course of lymphocytes and adult T-cell ...

for treating relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL) in adults, the agency announced on ...

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying ...

T-cell acute lymphoblastic leukemia (T-ALL) results from leukemic ... is associated with a favorable outcome in GRAALL-treated adult T-ALLs. We have recently established that the TLX1/3 ...

In T cell cancers such as T cell lymphoblastic leukemia (TLL), this challenge arises from fratricide, CAR T cell self-destruction. 1–3 CAR T cells often share the same receptors as malignant T cells, ...

While most people who are infected with HTLV-1 do not exhibit any symptoms, up to 5% of infected people will develop a type of leukemia called adult T-cell leukemia/lymphoma or a chronic neurological ...

A study of 783 patients treated with CAR T cell therapy found no evidence that the therapy itself caused secondary cancers.

A research team made a pivotal discovery in the field of cancer immunotherapy. The team identified a specific population of immune cells that play a critical role in successful treatment of relapsed ...

Patients with acute myeloid leukemia who relapse after stem cell transplantation have just a small chance of survival: doctors can give them additional donor T cells to fight the cancer, but only ...

Within a large group of more than 700 patients treated with CAR T cell therapy, researchers found no evidence that the therapy itself caused any type of secondary cancer in the modified T cells, ...

Boston – Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy for patients with acute myeloid leukemia (AML) who ...