The new compound provides a promising chemical scaffold to develop new potent anti-tuberculosis drugs. M. tuberculosis, the ...

This study aimed to calculate the incidence of AKI due to anti-TB drugs and analyze the outcomes and predictors of renal recovery. Methods: From 2006 to 2010, patients on anti-TB treatment were ...

Tuberculosis is a serious global health threat that infected more than 10 million people in 2022. Spread through the air and into the lungs, the pathogen that causes "TB" can lead to chronic cough, ...

A beneficial gut bacterium can tolerate high concentrations of first-line anti-tuberculosis (anti-TB) drugs, microbiologists at the Central Food Technological Research Institute in Karnataka have ...

The search for new tuberculosis drug targets under traditional laboratory methods has historically proven to be arduous and ...

They identified a total of 514 strains that were resistant to TB drugs, including both the old and the new treatment regimens. These highly drug-resistant strains were found in 27 countries across ...

The Health Ministry has dismissed media reports claiming a shortage of anti-tuberculosis (TB) drugs in India, labelling them as "incorrect and misleading". In a statement, the Ministry emphasised ...

Most bacteria have few, if any, P450s but we discovered that the TB bacterium has 20 different types." Even more exciting for the team was the knowledge that existing anti-fungal drugs already target ...

The researchers theorise the protective effects of these drugs could be because they reduce inflammation, control infections ...

TaBriX is a new spin-out company from The University of Manchester (UoM) with the mission to create novel anti-virulence drugs to fight difficult-to-treat infections. TaBriX’s initial focus is on the ...

[11] Because the elderly are more vulnerable to drug-induced AKI and usually have poor renal recovery, [14,15] AKI during anti-TB treatment may be more common and serious in Taiwan, where more ...

"It was therefore crucial to study how the TB bacteria would react to the global roll-out of this new regimen." The study examined in detail whether resistance to the drugs in the new regimen has ...