The CaSR is a G-protein coupled receptor that regulates calcium levels through its expression in the parathyroid gland and renal tubule. When calcium binds to the extracellular domain it induces a ...

Drawing from personal experience, Patty Keating advocates for greater awareness, improved diagnosis, and treatment among ...

Secondary hyperparathyroidism is a complex endocrine condition characterized by excess circulating parathyroid hormone (PTH) resulting from an underlying condition, most commonly chronic kidney ...

For instance, CaSR is known to regulate parathyroid hormone (PTH) release, which is vital for maintaining calcium levels. In cases of neonatal severe hyperparathyroidism (NSHPT), inherited defects ...

Calcimimetics suppress the secretion of parathyroid hormone by sensitizing ... binds to the extracellular portion of the calcium-sensing receptor and activates a cascade of intracellular signals ...

Calcium is an essential mineral that serves many roles in the body, including bone formation, muscle movement, nerve signaling, and heart rhythm regulation. A calcium blood test may be ordered as ...

01]), had a lesser total gland weight (531.8 mg ± 680.0 vs 1,039.6 mg ± 1,237.3; P < .01), and lesser 2-week parathyroid hormone (32.5 pg/mL ± 18.95 vs 41.0 pg/mL ± 27.8; P = .01). There was ...

There are four parathyroid glands, and they are normally about the size and shape of a grain of rice. They're usually behind the thyroid. In rare cases, the parathyroid glands exist in your ...

Yes, your body needs calcium. But can you get too much of a good thing? Calcium is the most abundant mineral in your body. You probably already know you need it for strong bones and teeth.

Study highlights calcium-to-magnesium ratio as a superior biomarker for nephrolithiasis in primary hyperparathyroidism.

Study of 2.4 million participants reveals potential advantages for cardiometabolic and psychiatric conditions alongside increased risks of gastrointestinal and musculoskeletal issues Study ...