Rubisco is the enzyme responsible for carbon fixation in plants, algae and many bacteria. A screen of a comprehensive library of rubisco variants (each with a different single-amino-acid mutation ...
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AI-Powered Enzyme Engineering Speeds Up Drug SynthesisIn a recent Nature study, researchers introduced a machine learning (ML)-assisted enzyme engineering platform that integrates cell-free DNA assembly, gene expression, and functional assays.
pH is a measure of how acidic or alkaline a solution is. The diagram below shows what happens to an enzyme when denaturation occurs. Each enzyme has an optimum pH but it also has a working range ...
The global enzyme-linked immunosorbent assay (ELISA) testing market size is evaluated at USD 2.42 billion in 2025 and is expected to reach around USD 4.19 billion by 2034, growing at a CAGR of 6.32% ...
The bimolecular fluorescence complementation (BiFC) assay has been widely used to examine interactions between integral and peripheral proteins within putative plasma membrane (PM) microdomains. In ...
We contend that microfluidic droplets offer a tractable platform for developing and standardizing a single-cell enzyme activity assay specifically adapted to handle the high diversity and ...
These radicals bind to proteins within close proximity to the APEX2 enzyme (∼20nm), and thus ... The PathHunter protein complementation assay (DiscoverX) using the PathHunter® HEK 293 CCR7 β-Arrestin ...
Modulation of Protein–Protein Interactions with Molecular Glues in a Synthetic Condensate Platform
Next to microscopic evaluation, we also developed a plate reader assay for the evaluation of molecular glues in condensates more compatible with classical high-throughput screening. Split luciferase ...
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