A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “A case report of donor cell–derived ...

Introducing individual mutations to mtDNA is challenging due to the large number of mitochondria within each cell. Instead, the researchers used a leukemia mouse model with a defective genetic ...

St. Jude researchers reveal that moderate levels of mitochondrial DNA mutations boost leukemia growth by increasing metabolic plasticity, while high mutation levels shut down tumor development. They ...

The genetics behind the progression of myelodysplasia to secondary acute myeloid leukemia (sAML) is poorly understood. In this study, we profiled somatic mutations and their dynamics using next ...

Chronic lymphocytic leukemia (CLL) tends to have a better outlook than most other types of leukemia. About 88% of adults over the age of 20 years live for 5 years post-diagnosis, and some can live ...

Kura and Kyowa used the announcement to confirm that they are on track to file a new drug approval application with the FDA ...

Kuro Oncology and partner Kyowa Kirin are on track for an NDA submission for ziftomenib in the second quarter of this year.

Given the frequent identification of somatic mutations in genes encoding regulators of transcription in leukemia and lymphoma, the Abdel-Wahab is especially focused on understanding the functional ...

Venetoclax, a selective Bcl-2 inhibitor, has proven effective in chronic lymphocytic leukemia (CLL), but genetic mutations or ...