Our findings reveal new mechanisms of dengue virus pathogenesis, which could pave the way for innovative approaches to tackle vector-borne viruses." In the future, the group plans to study the ...

Biological scientists have uncovered how the dengue virus uses its envelope protein to capture human plasmin from a blood meal to enhance the permeability of the mosquito midgut for infection.

This review discusses the epidemiology, burden and pathogenesis of dengue, as well as the vaccine candidates currently in clinical development. There is, therefore, an urgent unmet need for a safe ...

Dengue viral infections can result in a range of symptoms. Some people show no symptoms or just have mild signs of the disease, but others develop severe complications. How does the body respond ...

Dengue virus infections can result in a range of clinical manifestations from asymptomatic infection to dengue fever (DF) and the severe disease dengue haemorrhagic fever/dengue shock syndrome ...

Here, we review the most recent findings on the Crimean–Congo hemorrhagic fever virus molecular biology and pathogenesis, including aspects of virus–host cell interactions. To date ...

Mongkolsapaya et al. performed a detailed analysis of dengue virus-specific T-cell responses in Thai children with dengue. They observed that during acute infection, up to 7% ...

The NIH announced that it is launching a phase 2 human challenge trial of AV-1, an investigational monoclonal antibody to ...

The reemergence of dengue virus serotype 3 (DENV-3) in Brazil after 17 years could help worsen fresh outbreaks of the disease ...

If much more common viruses like dengue virus also target ANKLE2 ... “Thus, ZIKV’s unique pathogenesis derived from the NS4A-ANKLE2 interactions is from being in the wrong place at the ...

Researchers have uncovered how the dengue virus uses its envelope protein to hijack human plasmin to enhance transmission.