The cheapest way to get from Pittsburgh to Buffalo costs only $48, and the quickest way takes just 3¾ hours. Find the travel option that best suits you.

Track Miles (as of 06/2024) Owned/Leased/Operating Rights: 659 (New York - 122, Pennsylvania - 537) Interchanges

The best way to get from Buffalo to Pittsburgh is to bus via Youngstown which takes 5h 10m and costs $22 - $130. Alternatively, you can train, which costs $45 - $270 and takes 8h 42m, you could also fly, which costs $110 - $300 and takes 6h 18m.

The journey by Greyhound bus from Pittsburgh to Buffalo covers approximately 289 miles. The quickest trip duration is 7 hours 35 minutes, with at least 13 stops.

Train tickets from Pittsburgh to Buffalo start at $47, and the quickest route takes just 8h 18m. Check timetables and book your tickets with Rome2Rio.

Travel by bus from Pittsburgh to Buffalo in as little as 7 hours 50 minutes. Our daily bus leaves at 4:55 AM with free Wi-Fi, plan your perfect trip today with megabus.

Pittsburgh to Buffalo - Find the cheapest way with tickets starting at $22. Discover the fastest way by bus, car, train, or flight.

Travel hassle-free by train from Pittsburgh to Buffalo (NY) with tickets starting at $37. Check schedules, compare prices, and book now with Busbud!

How long is the drive from Pittsburgh, PA to Buffalo, NY? The total driving time is 3 hours, 18 minutes. Your trip begins in Pittsburgh, Pennsylvania. It ends in Buffalo, New York. If you're planning a road trip, you might be interested in seeing the total driving distance from Pittsburgh, PA to Buffalo, NY.