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Dengue Virus Evolution and Virulence Models - PMC
Dengue virus transmission has increased dramatically in the past 2 decades, making this virus one of the most important mosquito-borne human pathogens. The emergence of dengue …
Global evolutionary history and spatio-temporal dynamics of dengue …
Apr 5, 2017 · Dengue virus (DENV), a member of family Flaviviridae, is a positive-sense, single-stranded RNA virus. It has a genome size of approximately 11 kb, and the genome can be …
Structure of the dengue virus and evolution. (A) Dengue virus is ...
Dengue virus (DENV) is classified into four serotypes: DENV-1, DENV-2, DENV-3, and DENV-4 which are genetically-related but antigenically distinct types.
Antigenic evolution of dengue viruses over 20 years | Science
Nov 18, 2021 · We tracked the antigenic dynamics of each DENV serotype by using 1944 sequenced isolates from Bangkok, Thailand, between 1994 and 2014 (348 strains), in …
The history and evolution of human dengue emergence
Genetic studies suggest that all four serotypes of endemic/epidemic DENV evolved independently from ancestral, sylvatic viruses and subsequently became both ecologically and evolutionarily …
Dengue virus: Etiology, epidemiology, pathobiology, and …
Jan 1, 2025 · Dengue virus poses a global health threat, with approximately 390 million dengue infections occurring annually. This rapid spread is attributed to transportation and travel …
Intra-epidemic evolutionary dynamics of a Dengue virus type 1 ...
Mar 4, 2016 · In the current study, we present a micro-scale genetic analysis of a monophyletic lineage of DENV-1 genotype III (epidemic lineage) detected from November 2012 to May …
Understanding dengue virus evolution to support epidemic …
Understanding DENV evolution offers valuable opportunities to enhance surveillance and response to DENV epidemics via advances in RNA virus sequencing, bioinformatics, …
Molecular Evolution of Dengue Viruses: Contributions of …
Dengue viruses (DENV) are the most important arboviral pathogens in tropical and subtropical regions throughout the world, putting at risk of infection nearly a third of the global human …
Dengue and severe dengue - Fact sheet, March 2023 Dengue cases are occurring in more countries and growing every year. 2023 Dengue is present in over 100 countries Before 1970 …